The National Institutes of Health (NIH) is announcing a forthcoming funding opportunity titled "Collaborative Opportunities for Multiple-disciplinary, Bold, and Innovative Neuroscience (COMBINE)," aimed at fostering innovative research in neuroscience through collaborative team science. This initiative encourages applications from transdisciplinary teams of 3-6 principal investigators (PDs/PIs) to tackle complex research questions that can lead to significant advancements in the field, particularly in overcoming barriers and achieving paradigm shifts in neuroscience. The program is designed to support projects that integrate diverse expertise across basic, clinical, and translational neuroscience domains, with the goal of transforming knowledge and practice within a five-year timeframe. Interested applicants are encouraged to prepare for this opportunity, with an estimated synopsis posting date of February 4, 2026, and a closing date for applications expected on June 23, 2026. For further inquiries, potential applicants can contact the NINDS Team Science Group at NINDSteamscience@nih.gov or by phone at 240-328-3447.