Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
ID: 359648Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity for Resource-Related Research Projects aimed at developing models and methodologies for studying human health and diseases, specifically through the R24 grant mechanism, which does not allow clinical trials. This initiative, led by the Office of Research Infrastructure Programs (ORIP), seeks applications that focus on creating broadly applicable research models or new approach methodologies (NAMs) that address diseases impacting multiple organ systems, with a requirement that projects demonstrate relevance to two or more NIH Institutes or Centers. The NIH plans to allocate $5 million annually from fiscal years 2026 to 2029, funding at least six awards each year, with a maximum project duration of four years. Interested applicants, excluding foreign organizations, must complete federal registrations prior to submission and can direct inquiries to ORIPDCM@mail.nih.gov.

    Point(s) of Contact
    Files
    Title
    Posted
    The Department of Health and Human Services (NIH) is reissuing a funding opportunity (RFA-OD-25-010) for Resource-Related Research Projects (R24, Clinical Trials Not Allowed). This initiative, led by the Office of Research Infrastructure Programs (ORIP), encourages grant applications for developing, characterizing, or improving research models of human health and diseases, new approach methodologies (NAMs), or enhancing access to information about disease models. Projects must have broad applicability to two or more NIH Institutes or Centers (ICs) and evaluate diseases impacting multiple organ systems. Applications focusing on specific diseases or limited research areas will not be accepted. The NIH plans to commit $5,000,000 annually from FY 2026-2029, funding at least six awards per fiscal year, with a maximum project duration of four years. Eligible applicants include various organizations, but foreign organizations are excluded. All applicants must complete federal registrations, including SAM.gov and eRA Commons, prior to submission.
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