The National Institutes of Health (NIH) is announcing a funding opportunity for the Stroke Preclinical Assessment Network (SPAN) to support translational studies focused on acute cerebroprotection in experimental models of acute ischemic stroke. This initiative aims to establish a collaborative network comprising a Coordinating Center and up to six peer-reviewed data collection sites, emphasizing rigorous methodologies and replication in preclinical testing of stroke treatments. The estimated total program funding is $500,000, with one award expected to be made, and interested applicants are encouraged to prepare their proposals ahead of the anticipated Notice of Funding Opportunity (NOFO) release, which is expected to be published by December 2025. For further inquiries, potential applicants can contact Francesca Bosetti at 301-496-1297 or via email at frances@mail.nih.gov.