Limited Competition: Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)

Active
Yes
Status
Posted
Published Date
January 3rd, 2024
Close Date
September 1st, 2024
Opportunity No.
PAR-24-105

Agency

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Small Businesses

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Summary

The National Institutes of Health (NIH) has posted a grant opportunity titled "Limited Competition: Mutant Mouse Resource and Research Centers (U42 Clinical Trial Not Allowed)". This grant aims to support and advance the Mutant Mouse Resource and Research Centers (MMRRC), which play a crucial role in biomedical research. The MMRRC consortium is responsible for identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. These mutant mouse strains, along with related biomaterials, are used by researchers for various studies. The MMRRC consists of a regional network of four centers and an Informatics, Coordination and Service Center (ICSC). Together, they serve the needs of the biomedical research community by providing transgenic, knockout, and other genetically-engineered mutant mice. The MMRRC ensures that all strains meet high standards to optimize reproducibility of studies and maintain scientific rigor and transparency. Each MMRRC is also required to develop a small high-risk, high-return research pilot project that aligns with the goals and needs of the consortium. Small businesses are eligible to apply for this grant opportunity. However, non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply. For more information on eligibility criteria, please refer to the full Notice of Funding Opportunity. The deadline for submitting applications is September 1, 2024. Interested applicants can find additional information and apply through the following link: http://grants.nih.gov/grants/guide/pa-files/PAR-24-105.html. For any inquiries, please contact NIH Grants Information at grantsinfo@nih.gov.

Description

This Notice of Funding Opportunity (NOFO) invites applications for the continued support and advancement of the Mutant Mouse Resource and Research Centers (MMRRC). The MMRRC consortium is expected to facilitate research by identifying, acquiring, evaluating, characterizing, cryopreserving, and distributing mutant mouse strains to qualified biomedical investigators. A regional network of four MMRRCs and an Informatics, Coordination and Service Center (ICSC) collectively serve the needs of the biomedical research community for transgenic, knockout and other genetically-engineered mutant mice and related biomaterials. MMRRC strains are held to the highest standards to optimize reproducibility of studies and assure scientific rigor and transparency; all submitted strains are thoroughly reviewed and documented and include additional quality control measures. The Program Director/Principal Investigator (PD/PI) of each MMRRC in addition to the major resource activities is required to develop a small high risk, high return, research pilot project that complements the goals and needs of the MMRRC consortium.

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