The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement aimed at strengthening national laboratory and HIV epidemiologic monitoring capacities in the Kingdom of Eswatini under the PEPFAR initiative. The primary objective of this funding opportunity is to enhance the country's response to HIV, TB, and related public health threats by improving laboratory systems, diagnostic operations, and epidemic monitoring capabilities. This initiative is crucial for ensuring timely and accurate diagnosis and management of these diseases, thereby contributing to health security benchmarks in Eswatini. Interested applicants can reach out to the CDC at pepfarfoas@cdc.gov, with an anticipated funding amount of $5,000,000 for the first year, and applications are due by February 17, 2026, with awards expected to be announced by September 30, 2026.

The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $5,000,000 for Year 1, subject to the availability of funds.The goal of this NOFO is to engage with the Government of the Kingdom of Eswatini to strengthen national laboratory and HIV epidemic monitoring systems to enhance an efficient, resilient, and self-reliant response to HIV, TB, and related public health threats. To facilitate timely and accurate HIV and TB diagnosis and management, activities will focus on supporting the national laboratory system to enhance diagnostic network operations, optimize national sample referral systems, advance interoperability of laboratory and clinical information system, and ensure testing quality through local proficiency testing and laboratory certification schemes. Support will also be provided to strengthen the capacity of the Ministry of Health and other relevant government entities to oversee, conduct, and advance HIV and TB epidemic monitoring necessary to inform life-saving program interventions. The technical assistance aimed at enhancing national laboratory and disease monitoring systems, as well as workforce capacity, should show progress toward health security benchmarks. These benchmarks will indicate that Eswatini has established self-reliant systems, structures, policies, and a workforce capable of preparing for, identifying, and responding to concerning signals in HIV, TB, and related public health threats.

Strengthening national laboratory and HIV epidemiologic monitoring capacities and systems to enhance an efficient, resilient and self-reliant response to HIV, TB and related public health threats in the Kingdom of Eswatini under PEPFAR

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