Drug-Free Communities (DFC) Support Program - (Year 6 - FY25 Cohort)
Grant Opportunity Analysis
The Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC), is accepting applications for the Drug-Free Communities (DFC) Support Program for Fiscal Year 2026. This grant opportunity aims to establish and strengthen community coalitions focused on preventing and reducing substance use among youth, specifically targeting individuals aged 18 and younger. Eligible applicants include community-based coalitions that have previously received DFC funding, have experienced a lapse in funding, or are applying for a second five-year funding cycle, with a requirement to demonstrate a 12-sector coalition and a mission statement addressing youth substance use prevention. The total estimated funding for this program is $50 million, with individual awards capped at $125,000 annually, and a 100% matching funds requirement from non-federal sources. Applications must be submitted electronically by 11:59 PM ET on February 12, 2026, and interested parties can contact Christi Jones at DFC_NOFO@cdc.gov for further information.
Eligible Applicants
Eligible applicants are community-based coalitions addressing youth substance use that have previously received a DFC grant (Year 1–5), have experienced a lapse in funding, or have concluded the first five-year funding cycle and are applying for a second five-year funding cycle. Applicants must be a nonprofit (as defined by the IRS as a 501(c) organization); or an entity that the Administrator determines to be appropriate; or part of, or is associated with an established legally recognized domestic, public or private nonprofit organization. For example, state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Pub. L. No. 94-437), public or private universities and colleges, professional associations, voluntary organizations, self-help groups, consumer and provider services-oriented constituency groups, community- and faith-based organizations, and tribal organizations. (Pub. L. No. 114-198 Sec 103). For the purposes of this NOFO and the DFC Support Program, a coalition is defined as a community-based formal arrangement for cooperation and collaboration among groups or sectors of a community in which each group retains its identity, but all agree to work together toward a common goal of building a safe, healthy, and drug-free community. In furtherance of the Trump Administration's Statement of Drug Policy Priorities, the DFC Support Program is committed to protecting American youth from the dangers of drug use. DFC Support Program applicants are expected to support applicable Executive Orders, including but not limited to: Executive Order 14168: Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government, Executive Order 14159: Protecting the American People from Invasion, Executive Order 14173: Ending Illegal Discrimination and Restoring Merit-Based Opportunity, Executive Order 13768: Enhancing Public Safety in the Interior of the United States, Executive Order 14182: Enforcing the Hyde Amendment.