Controlling and Preventing STIs in US Health Departments (CAP-STIs)
Grant Opportunity Analysis
The Centers for Disease Control and Prevention’s National Center for HIV, Viral Hepatitis, STD, and TB Prevention is offering a cooperative agreement to support state, district, territorial, and some city or county health departments in controlling and preventing sexually transmitted infections. The program funds work to track, prevent, and control syphilis, gonorrhea, and chlamydia, with activities aligned to reducing adverse outcomes, improving prevention technology adoption, and coordinating integrated STI response efforts. Priority is driven by local surveillance data and focuses on populations disproportionately impacted by STI transmission, with eligible cities needing demonstrated surveillance reporting capacity and coordination with their parent state; CDC may fund a limited number of cities competitively while states are funded by formula. The opportunity is CFDA 93.977, has an estimated total program funding of $500,000,000 and 59 awards, and electronically submitted applications are due by 11:59 p.m. ET on August 29, 2026.
Eligible Applicants
All fifty (50) states, the District of Columbia, the US Virgin Islands and Puerto Rico are eligible to apply. To ensure implementation of STI control and prevention nationwide, CDC intends to fund all fifty states, the District of Columbia, the US Virgin Islands and Puerto Rico, non-competitively, according to a funding formula based on the respective jurisdiction"s population & morbidity of three reportable STIs (chlamydia, gonorrhea and primary & secondary syphilis).Section 318(c) of the Public Health Services Act, 42 USC 247c(c), provides that the Secretary of HHS may provide funding to "States and, in consultation with the State health authority, to political subdivisions of States..." to conduct STI prevention & control projects. This language allows CDC to fund cities in addition to their respective states. Under the previous STI prevention & control funding opportunity PS19-1901 (& prior to that, PS14-1402), CDC funded the following cities based upon population, STI morbidity & organizational capacity: New York City, Philadelphia, Baltimore, Chicago, Los Angeles & San Francisco.To maximize the efficiency of program delivery, CDC may again fund a limited number of cities under this award. Funding for cities will be awarded competitively, based on the same criteria shown above for the state formula: population, STI morbidity, as well as organizational capacity. Directly funded cities must have a demonstrated capacity to report chlamydia, gonorrhea and syphilis surveillance data to CDC; an agreement with their parent state to apply separately for NOFO funding & to coordinate/collaborate appropriately following any funding; & data showing that the surrounding metropolitan statistical area (MSA) reported 2024 data showing:> or = to 500 cases of syphilis aged 15-44 reported in 2024 > or = 7500 cases of gonorrhea aged 15-44 reported in 2024 > or = to 15,000 cases of chlamydia aged 15-44 reported in 2024 > or = to 4 million residents estimated in 2024 Cities that apply for funding must submit their 2024 surveillance summary demonstrating the number of required cases & residents, a joint statement of collaboration/coordination with their respective state, or a letter indicating the city has notified the state of its application for funding of this award. In the event that cities do not compete successfully for the funding, all funds will be provided to the state, which will be responsible for distributing funds to its constituent cities as appropriate.
Grant Documents
No documents available for this grant.