NIH Director's Transformative Research Award (R01 Clinical Trial Optional)
Grant Opportunity Analysis
The National Institutes of Health is seeking applications for the NIH Director's Transformative Research Award to support pioneering and unconventional scientific research. Awardees will conduct bold research projects that have the potential to create new scientific paradigms, establish novel clinical approaches, or develop transformative technologies. This discretionary grant program, which is part of the NIH Common Fund's High-Risk, High-Reward Research Program, does not require cost-sharing or matching funds. The agency expects to make approximately six awards, with projects estimated to start on September 30, 2028. Applications must be submitted by the estimated close date of September 3, 2027, and inquiries can be directed to Transformative_Awards@mail.nih.gov.
Eligible Applicants
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Grant Documents
No documents available for this grant.