Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Grant Opportunity Analysis
The National Institutes of Health and the National Institute of Allergy and Infectious Diseases are seeking cooperative agreement applications to fund the research and development of medical countermeasures and technologies against radiological, nuclear, or chemical threats. Funded projects must focus on advancing the understanding of exposure natural history, developing injury models, validating biodosimetry and diagnostic tools, or supporting the Nonhuman Primate Radiation Survivor Cohort. Eligible applicants include domestic higher education institutions, nonprofits, and for-profit organizations, and proposed projects must exclude clinical trials as well as foreign subawards. NIAID intends to commit $15 million in fiscal year 2027 to fund up to 21 awards for project periods lasting up to five years. Applications are due annually on November 9 in 2026, and October 8 or 9 in subsequent years through the final closing date of October 9, 2028.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.