The Centers for Disease Control and Prevention (CDC) is inviting applications for the Drug-Free Communities (DFC) Support Program grants for Fiscal Year 2026, aimed at preventing youth substance use. This program seeks to establish and strengthen collaborations among community coalitions, public and private non-profit agencies, and government entities to reduce substance abuse among youth and, over time, among adults by addressing community risk factors. The DFC Support Program is critical for fostering safe and healthy communities, with an estimated total funding of $31,250,000 available for approximately 50 awards, each ranging from $0 to $125,000. Interested applicants, particularly community-based coalitions that have not previously received a DFC grant, must submit their applications electronically by April 14, 2026, with awards expected to be announced by August 31, 2026. For further inquiries, applicants can contact Christi Jones at DFC_NOFO@cdc.gov.