Drug-Free Communities (DFC) Support Program – NEW (Year 1)
Grant Opportunity Analysis
The Centers for Disease Control and Prevention (CDC), through the National Center for Injury Prevention and Control (NCIPC), is offering a grant opportunity under the Drug-Free Communities (DFC) Support Program for Fiscal Year 2026. This program aims to fund community-based coalitions that focus on preventing and reducing substance use among youth, with a requirement for applicants to demonstrate a coalition of at least 12 sectors and a mission statement dedicated to youth substance use prevention. The DFC Support Program is critical in addressing the rising concerns of youth substance abuse by fostering collaboration among various community stakeholders and implementing evidence-based practices. Interested applicants must submit their proposals by April 14, 2026, with each grant award ranging up to $125,000 annually for a five-year period, requiring a 100% non-federal match. For further inquiries, applicants can contact Christi Jones at DFC_NOFO@cdc.gov.
Eligible Applicants
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educations. A DFC legal applicant (an organization applying on behalf of a coalition, the coalition, or the applicant coalition) must reside within the United States and/or the U.S. territories. Additional Information on Eligibility: Eligible applicants are community-based coalitions addressing youth substance use that have not yet previously received a DFC grant. Applicants must be a nonprofit (as defined by the IRS as a 501(c) organization); or an entity that the Administrator determines to be appropriate; or part of, or is associated with an established legally recognized domestic, public or private nonprofit organization. For example, state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Pub. L. No. 94-437), public or private universities and colleges, professional associations, voluntary organizations, self-help groups, consumer and provider services-oriented constituency groups, community- and faith-based organizations, and tribal organizations. (Pub. L. No. 114-198 Sec 103). For the purposes of this NOFO and the DFC Support Program, a coalition is defined as a community-based formal arrangement for cooperation and collaboration among groups or sectors of a community in which each group retains its identity, but all agree to work together toward a common goal of building a safe, healthy, and drug-free community. In furtherance of the Trump Administration"s Statement of Drug Policy Priorities, the DFC Support Program is committed to protecting American youth from the dangers of drug use. DFC Support Program applicants are expected to support applicable Executive Orders, including but not limited to: Executive Order 14168: Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government, Executive Order 14159: Protecting the American People from Invasion, Executive Order 14173: Ending Illegal Discrimination and Restoring Merit-Based Opportunity, Executive Order 13768: Enhancing Public Safety in the Interior of the United States, Executive Order 14182: Enforcing the Hyde Amendment