GrantPostedDiscretionary

NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

National Institutes of Health
RFA-RM-28-004
Application Deadline
—
Days Remaining
—
Until deadline
Award Ceiling
$350,000
Total Program Funding
$5,700,000

Grant Opportunity Analysis

The National Institutes of Health is seeking applications for the NIH Director's Early Independence Award to support outstanding early-career investigators. This grant is designed to accelerate the transition to an independent research career by allowing select investigators to bypass the traditional postdoctoral training period and immediately pursue independent research. Applicants from all scientific fields relevant to the NIH mission are welcome, and the program encourages projects that fall under the High-Risk, High-Reward Research Program. The agency expects to make approximately 10 awards, each with an annual award ceiling of $350,000 in direct costs, for an estimated total program funding of $5,700,000. Applications must be submitted by the estimated close date of September 10, 2027, and questions can be directed to the program office via email at EarlyIndependence@od.nih.gov.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grant Documents

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Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedSep 3, 2026

Funding Details

Award Ceiling
$350,000
Award Floor
$350,000
Est. Total Program Funding
$5,700,000
Expected Awards
10
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

Name
NIH Director's Early Independence Award Program

CFDA Numbers

93.310

Official Sources