Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Grant Opportunity Analysis
The National Institutes of Health intends to publish a Notice of Funding Opportunity to solicit cooperative agreement applications to develop and implement investigator-initiated multi-site clinical trials, including efficacy, effectiveness, pragmatic, and implementation research. Applicants must deliver a comprehensive scientific and operational plan for the trial, alongside a coordination plan for project administration, data management, and biostatistical support. The funding will utilize a bi-phasic, milestone-driven UG3/UH3 mechanism consisting of a start-up phase of up to two years and a full clinical trial implementation phase of up to five years, for a total award duration of up to seven years. The estimated synopsis post date is November 16, 2026, with an estimated close date of February 16, 2027, and interested parties can contact the NHLBI Division of Cardiovascular Sciences at NHLBIDCVSClinical@mail.nih.gov.
Eligible Applicants
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Grant Documents
No documents available for this grant.