The Department of the Army, through the US Army Medical Research and Materiel Command (USAMRAA), is offering the FY25 Breast Cancer Breakthrough Award Level 3, aimed at supporting innovative research with the potential to significantly advance breast cancer treatment and prevention. Applicants are required to address at least one of the Department of Defense-defined challenges related to breast cancer, and the research team must include breast cancer consumer advocates to ensure patient perspectives are integrated into the research process. This grant program allocates approximately $27.9 million for three awards, with funding caps of $4 million for single Principal Investigators and $5 million for projects involving a Partnering PI. Pre-applications are due by June 13, 2025, and full applications must be submitted by September 10, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.