DoD Breast Cancer Breakthrough Award Level 3

The Department of Defense (DOD) announces the FY25 Breast Cancer Research Program (BCRP) Breakthrough Award Level 3, seeking applications for innovative research that promises significant advancements in breast cancer treatment and prevention. The program, with a funding opportunity number HT942525BCRPBTA3, allocates approximately $27.9 million for three awards, with a direct cost cap of $4 million for single Principal Investigators (PIs) and $5 million under a Partnering PI option. Pre-applications must be submitted by June 13, 2025, with full applications due by September 10, 2025. Eligibility extends to both extramural and intramural organizations, encouraging collaborations among academic, industry, and military entities. Key application components include a pre-application narrative addressing DOD-defined challenges, detailed project plans, and the inclusion of breast cancer consumer advocates in the research team. Notably, the funding prioritizes research that can lead to breakthroughs in patient outcomes and tackles significant challenges in breast cancer, including prevention, early detection, and innovative treatment methodologies. The process is structured as a two-step application, necessitating compliance with submission protocols and review criteria laid out for both the pre-application and full application phases.