Kidney Precision Medicine Project Central Hub
ID: 359197Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/359197
Timeline
    Description

    The National Institutes of Health (NIH) is seeking applications for the Kidney Precision Medicine Project Central Hub through a cooperative agreement aimed at advancing research in chronic kidney diseases (CKDs) and acute kidney injuries (AKIs). This initiative, which builds on the existing Kidney Precision Medicine Project (KPMP) established in FY2017, aims to enhance participant recruitment and tissue interrogation, with a focus on discovering novel molecular pathways related to kidney health. The total estimated funding for this opportunity is $5 million, with one award anticipated, and interested applicants can reach out to Debbie S. Gipson at Debbie.Gipson@nih.gov or by phone at 301-480-2268 for further information. Key deadlines include an estimated synopsis post date of July 5, 2026, and a close date of October 5, 2026, with the project expected to commence on July 1, 2027.

    Point(s) of Contact
    Debbie S. Gipson, MS, MD National Institute of Diabetes and Digestive and Kidney Diseases
    (301) 480-2268
    Debbie.Gipson@nih.gov
    Files
    No associated files provided.
    Similar Opportunities
    Kidney Precision Medicine Project Central Hub (U24 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the Kidney Precision Medicine Project Central Hub (U24 Clinical Trial Not Allowed), aimed at supporting the KPMP cohort through the collection and de-identification of clinical data and samples. The project seeks to establish a Central Hub that will collaborate with various sites to evaluate kidney biopsies from participants with acute kidney injury or chronic kidney disease, ultimately creating a Kidney Tissue Atlas and identifying critical components for novel therapies. This cooperative agreement has an estimated total funding of $5 million, with one award expected, and applications are due by October 5, 2026. For further inquiries, interested applicants can contact Debbie S. Gipson at Debbie.Gipson@nih.gov or by phone at 301-480-2268.
    Kidney Precision Medicine Project Tissue Interrogation Sites (U01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the Kidney Precision Medicine Project (KPMP) - Tissue Interrogation Sites (TIS) through a cooperative agreement, aimed at analyzing human kidney tissue. The primary objective is to collaborate with various sites to obtain and evaluate kidney biopsies from participants suffering from acute kidney injury (AKI) or chronic kidney disease (CKD), ultimately creating a Kidney Tissue Atlas and identifying critical disease subgroups and therapeutic targets. This initiative is crucial for advancing kidney disease research and developing novel therapies, with an estimated total program funding of $6 million and an expected seven awards to be made. Interested applicants can reach out to Debbie S. Gipson at Debbie.Gipson@nih.gov or by phone at 301-480-2268, with applications due by October 5, 2026, and project start anticipated on July 1, 2027.
    Kidney Precision Medicine Project Tissue Interrogation Sites
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the Kidney Precision Medicine Project (KPMP) Tissue Interrogation Sites through a cooperative agreement. This initiative aims to continue the KPMP, which focuses on the ethical collection and analysis of human kidney biopsy tissue to uncover molecular pathways related to Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs). The project is significant for advancing kidney disease research and enhancing participant recruitment, with an estimated total funding of $6 million to support up to 14 awards for recruitment and tissue interrogation sites. Interested applicants can reach out to Debbie S. Gipson at Debbie.Gipson@nih.gov or call 301-480-2268 for further information, with proposals due by October 5, 2026, and project start anticipated on July 1, 2027.
    Kidney Precision Medicine Project Recruitment Sites
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for the Kidney Precision Medicine Project (KPMP) Recruitment Sites through a cooperative agreement. This initiative aims to continue the KPMP, which focuses on collecting and analyzing human kidney biopsy tissue to uncover molecular pathways related to Chronic Kidney Diseases (CKDs) and Acute Kidney Injuries (AKIs), with an emphasis on enhancing participant recruitment and tissue interrogation. The program anticipates awarding approximately $4 million across seven grants, with applications expected to be submitted by September 15, 2026, and awards anticipated to be made by June 1, 2027. Interested applicants can reach out to Debbie S. Gipson at Debbie.Gipson@nih.gov or call 301-480-2268 for further information.
    Kidney Precision Medicine Project Recruitment Sites (U01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the Kidney Precision Medicine Project Recruitment Sites (U01 Clinical Trial Not Allowed), aimed at enrolling participants with acute kidney injury (AKI) and/or chronic kidney disease (CKD) into a longitudinal cohort study. The selected recruitment sites will collaborate with various entities to conduct protocol-based kidney biopsies, create a Kidney Tissue Atlas, and identify critical disease subgroups and therapeutic targets. This initiative is crucial for advancing kidney disease research and developing novel therapies, with an estimated total program funding of $4 million and an expected seven awards to be made. Interested applicants can reach out to Debbie S. Gipson, MS, MD at Debbie.Gipson@nih.gov or call 301-480-2268 for further information, with applications due by October 5, 2026, and project start anticipated on July 1, 2027.
    Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is seeking applications for a cooperative agreement to continue the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (SDRC), which is part of a clinical trial consortium aimed at improving care for patients recovering from acute kidney injury (AKI). The objective is to extend the current study for three years to meet enrollment targets, complete participant follow-up, and facilitate data analysis and dissemination of findings, ultimately contributing to the development of standard care practices for Stage 2 and 3 AKI survivors. This initiative is critical as there is currently no established standard of care for patients post-hospitalization with AKI, and the insights gained are expected to significantly enhance clinical management strategies. The estimated total program funding is $1,000,000, with one award anticipated, and interested applicants should contact Ivonne Schulman at ivonne.schulman@nih.gov or 301.435.3350 for further details. Key deadlines include an estimated synopsis close date of July 1, 2026, and an expected project start date of February 1, 2027.
    Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for a limited competition grant titled "Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers," which requires a clinical trial. This opportunity aims to extend the COPE-AKI clinical trial consortium for three years, focusing on meeting enrollment targets, completing participant follow-up, and facilitating data analysis to enhance clinical management strategies for patients recovering from acute kidney injury (AKI). The successful completion of this study is expected to inform the development of standard care practices for Stage 2 and 3 AKI survivors, addressing a significant gap in current healthcare. The estimated total program funding is $2.5 million, with three awards anticipated, and interested applicants can reach out to Ivonne Schulman at ivonne.schulman@nih.gov or by phone at 301-435-3350. Key deadlines include the synopsis posting on April 1, 2026, application closing on July 1, 2026, and the anticipated project start date on February 1, 2027.
    Notice of Intent to Publish a Funding Opportunity Announcement for Precision Medicine for Type 1 Diabetic Nephropathy (U01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for a cooperative agreement aimed at advancing research on Type 1 Diabetic nephropathy (T1D). This initiative seeks applications from Recruitment Sites (RS) to enroll adult and pediatric patients with T1D, particularly those at high risk for diabetic nephropathy, into a longitudinal cohort study, which will include protocol-based kidney biopsies. The research will leverage existing resources from the Kidney Precision Medicine Project (KPMP) to create a Kidney Tissue Atlas, identify disease subgroups, and explore novel therapeutic targets. The estimated total program funding for this opportunity is $1.3 million, with the NOFO expected to be published in fall 2024 and applications due in late fall 2024. Interested applicants are encouraged to reach out to the NIDDK contacts provided in the announcement for further information.
    Kidney, Urologic, and Hematologic Diseases - Fostering the AdvanceMent of an Interactive Learning communitY - Coordinating Center (KUH-FAMILY)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Kidney, Urologic, and Hematologic Diseases - Fostering the AdvanceMent of an Interactive Learning communitY - Coordinating Center (KUH-FAMILY)." This initiative aims to establish a Coordinating Center that will unify and enhance various training and career development programs focused on recruiting, training, and retaining a national community of researchers in kidney, urologic, and hematologic diseases. The program is critical for fostering collaboration and innovation within these health fields, ultimately contributing to improved research outcomes. The estimated total funding for this cooperative agreement is $2,000,000, with one award expected to be made. Interested applicants can reach out to Christine Maric-Bilkan via email at christine.maric-bilkan@nih.gov for further information, with key deadlines including a synopsis close date of July 1, 2026, and an estimated project start date of February 1, 2027.
    Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites." This cooperative agreement aims to support the continuation of the CURE Consortium, which focuses on understanding the causes and potential interventions for Chronic Kidney Disease of Uncertain Etiology (CKDu) affecting agricultural communities, particularly in low and middle-income countries. The research is crucial as CKDu poses significant health risks, leading to kidney failure among young working-age populations, and the findings will have implications for kidney health in the U.S. The estimated total program funding is $6 million, with five awards expected, and applications are due by July 1, 2026. For further inquiries, interested parties can contact Susan Mendley at susan.mendley@nih.gov or by phone at 301.827.1861.