HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Clinical Trial Center and Clinical Centers (U01 Clinical Trial Optional)
Grant Opportunity Analysis
The National Institutes of Health (NIH) is set to announce a funding opportunity titled "HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials," aimed at establishing a Clinical Trial Center (CTC) and up to seven Clinical Centers (CCs) focused on heart failure with preserved ejection fraction (HFpEF). The initiative seeks to coordinate precision clinical trial activities, including master protocol development, project management, and recruitment oversight, while the CCs will be responsible for recruiting and retaining heart failure patients and conducting deep phenotyping protocols. This program is crucial for advancing personalized treatment approaches in heart failure, and while applications are not currently being solicited, interested parties are encouraged to prepare collaborative proposals ahead of the estimated synopsis posting on October 15, 2025, with a projected award date of May 1, 2026. For further inquiries, applicants can contact the HeartShare Team via email at nhlbiheartshare@mail.nih.gov.
Eligible Applicants
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).