The National Institutes of Health (NIH) is offering a cooperative agreement opportunity for the establishment of the Data Coordinating Center (DCC) for the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC). The DCC will play a crucial role in coordinating collaborations among genetic research centers, managing participant enrollment, biospecimen collections, and overseeing data submission to central databases, all aimed at advancing research in inflammatory bowel disease (IBD). This initiative is vital for improving medical management and precision medicine for IBD patients, as it seeks to develop new predictors of disease outcomes through the integration of genetic, clinical, and environmental data. The estimated total funding for this program is $1,600,000, with one award expected to be made. Interested applicants can reach out to Dr. Ludmila Pawlikowska at Ludmila.pawlikowska@nih.gov or by phone at 301-480-9372 for further information. The application period is open until November 1, 2026, with an anticipated award date of July 1, 2027.

The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) seeks to advance its mission by continuing the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC). The IBDGC has led collaborative efforts resulting in the identification of &gt;300 genetic risk loci for different IBD subtypes across patient populations and characterization of underlying biological mechanisms. Despite advances in biological understanding and the development of a range of biologic therapies, IBD remains a chronic, severe and heterogenous disease with no cure requiring multiple interventions over the life course. Diagnostic biomarkers and accurate predictors of critical outcomes including disease remission, recurrence, and response to specific therapies are lacking. The IBDGC will leverage patient cohorts, biospecimens and advances in data science to characterize the interactions of genetic, clinical and environmental factors in disease development and progression, and to develop new predictors of disease outcomes, with the goal of improving medical management and advancing precision medicine for IBD patients. The Data Coordinating Center (DCC) of the IBDGC will coordinate collaboration among IBDGC Genetic Research Centers (described in the companion notice), external scientific collaborations and pilot projects, participant enrollment, biospecimen collections and processing, and manage the submission of data and samples to central databases and repositories. 

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