Advancing Global Health

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement (APS) titled “Advancing Global Health” (DFOP0017890). This open competition seeks organizations to implement projects that operationalize the America First Global Health Strategy, complementing existing bilateral Memoranda of Understanding (MOUs) with partner governments. The program aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety and prosperity. Awards can range from $500,000 to $250 million, with total estimated funding up to $4.5 billion. Eligible applicants include U.S. and foreign for-profit, non-profit, higher education, public international organizations, and governmental institutions. Submissions are accepted as Statements of Interest (SOIs) in response to specific Addenda released quarterly, with rolling application deadlines. SOIs must describe the problem, proposed solution, anticipated outcomes, and partner roles. Full applications are by invitation only after an SOI review. Cost-sharing is not required but may be discussed during co-design. Specific funding restrictions apply, including prohibitions against supporting terrorist organizations, foreign security forces implicated in human rights violations, UNRWA, activities encouraging mass migration caravans, and the use of FASC-prohibited unmanned aircraft systems. Compliance with various federal regulations, including anti-discrimination and trafficking in persons laws, is mandatory. Applicants must have a Unique Entity Identifier (UEI) and SAM.gov registration for full applications, though not for initial SOI submission. Review criteria include program idea quality, organizational capacity, and ability to achieve objectives.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) is launching an Annual Program Statement (APS) called "Advancing Global Health" (DFOP0017890). This initiative seeks organizations to implement projects aligning with the America First Global Health Strategy, focusing on bilateral Memoranda of Understanding (MOUs) with partner governments. The program aims to save lives, strengthen health systems, and foster self-reliance. Multiple awards, ranging from $500,000 to $250 million, will be granted over a period of up to five years, with total estimated funding up to $4.5 billion. Eligible applicants include U.S. and foreign for-profit enterprises, higher education institutions, faith-based organizations, Public International Organizations, and governmental institutions. The application process involves a two-phase submission: first, a Statement of Interest (SOI) in response to specific Addenda issued quarterly, followed by a full application for selected SOIs. While cost-sharing is not required, a Unique Entity Identifier (UEI) and SAM.gov registration are mandatory for full applications. The APS outlines detailed submission requirements, review criteria, funding restrictions, and post-award administrative and reporting requirements.

The Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement (APS) titled "Advancing Global Health" (DFOP0017890). This open competition seeks organizations to implement projects that operationalize the America First Global Health Strategy, complementing bilateral Memoranda of Understanding (MOUs) with partner governments. Projects aim to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and benefit U.S. safety and prosperity. Funding ranges from $500,000 to $250 million, with up to $4.5 billion available, supporting up to 100 awards over five years. Eligible applicants include U.S. and foreign for-profit, non-profit, higher education institutions, Public International Organizations, and governmental entities. The application process involves a two-phase submission: a Statement of Interest (SOI) in response to specific Addenda, followed by a full application for selected concepts. SOIs are reviewed quarterly, and selected applicants may engage in co-design with the Department of State. Rigorous eligibility, submission, and review criteria apply, including compliance with federal regulations and restrictions on funding activities that support terrorism, human rights violations, or mass migration. Successful applicants will receive a grant or cooperative agreement and must comply with post-award reporting requirements.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement (APS) titled "Advancing Global Health," opportunity number DFOP0017890. This open competition invites eligible organizations to submit Statements of Interest (SOIs) to implement projects supporting the America First Global Health Strategy. The strategy aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety and prosperity. Awards can range from $500,000 to $250 million, with total estimated funding up to $4.5 billion over five years. SOIs are submitted in response to specific Addenda released quarterly, outlining GHSD priorities. Eligible applicants include U.S. and foreign private for-profit enterprises, higher education institutions, faith-based organizations, Public International Organizations, and governmental institutions. While cost-sharing is not required, a Unique Entity Identifier (UEI) and SAM.gov registration are necessary for full applications. The review process involves a merit review panel for SOIs, with selected applicants invited to submit full proposals.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) invites organizations to submit Statements of Interest (SOI) for projects supporting rapid responses to infectious disease outbreaks. This addendum, titled "Rapid Outbreak Response" under the "Advancing Global Health" funding opportunity (DFOP0017890), seeks proposals to advance Pillar One of the America First Global Health Strategy: Making America Safer, with goals to detect outbreaks within seven days and contain them at their source. Up to 10 awards, totaling $290 million, are anticipated for projects focusing on speed, operational readiness, and flexibility, with a completion timeframe of five years or less. Key objectives include rapid activation and surge response, early detection and containment, coordinated response, and reinforcement of country systems. Projects must align with guiding principles such as speed, country ownership, targeted resource use, evidence-informed decision-making, coordination, and sustainability.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement Addendum titled “Rapid Outbreak Response.” This addendum invites organizations to submit Statements of Interest (SOIs) for projects aimed at supporting countries in responding comprehensively to infectious disease outbreaks. The initiative aligns with Pillar One of the America First Global Health Strategy, focusing on rapid detection and containment of outbreaks to protect U.S. health and economy. Projects will prioritize swift activation, operational readiness, and flexibility, supporting immediate response actions across various technical and operational domains, including coordination, medical countermeasures, immunization, and surveillance. The goal is to enable rapid, effective, and coordinated outbreak response, reducing morbidity, mortality, and cross-border spread. The addendum outlines objectives such as rapid activation and surge response, early detection and containment, coordinated response, and system reinforcement. Key guiding principles include speed, country ownership, targeted resource use, risk-based decision-making, coordination, and sustainability. The deadline for questions is March 27, and SOIs are due by May 31. Up to 10 awards are anticipated, with total estimated funding up to $290 million, subject to availability, for projects lasting five years or less.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an addendum to its "Advancing Global Health" Annual Program Statement, inviting Statements of Interest (SOIs) for Rapid Outbreak Response (ROR) projects. The initiative aims to support countries in effectively responding to infectious disease outbreaks, aligning with Pillar One of the America First Global Health Strategy: Making America Safer. The program seeks to enable outbreak detection within seven days and contain outbreaks at their source before they reach the U.S. Up to $290 million is available for approximately 10 awards, with projects to be completed within five years. Key objectives include rapid activation and surge response, early detection and containment, coordinated response, and reinforcement of country systems. Projects must prioritize speed, country ownership, targeted resource use, evidence-informed decision-making, coordination, and sustainability.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an addendum to its "Advancing Global Health" Annual Program Statement, inviting Statements of Interest (SOIs) for Rapid Outbreak Response (ROR) projects. This initiative, aligned with the America First Global Health Strategy, aims to support countries in rapidly responding to infectious disease outbreaks to contain them at their source and prevent pandemics. Projects should focus on immediate response actions during the earliest stages of an outbreak, prioritizing speed, operational readiness, and flexibility. Key objectives include rapid activation, early detection and containment, coordinated response, and reinforcement of country systems for sustained health security. Up to 10 awards, totaling an estimated $290 million, are anticipated for projects to be completed in five years or less. SOIs are due by May 31, 2024.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement Addendum for Rapid Outbreak Response (ROR). This initiative invites organizations to submit Statements of Interest (SOIs) for projects supporting countries in responding to infectious disease outbreaks. The goal is to advance rapid outbreak response in line with the America First Global Health Strategy, aiming to detect outbreaks within seven days and contain them at their source to protect Americans and the economy. The program seeks to enable timely, effective responses by supporting immediate actions during the earliest stages of an outbreak. Projects should prioritize speed, operational readiness, flexibility, and coordination, covering areas like incident management, medical countermeasures, immunization, and surveillance. The addendum anticipates up to 10 awards with an estimated total funding of up to $290 million, with projects to be completed in five years or less. Key objectives include rapid activation, early detection and containment, coordinated response, and system reinforcement. Guiding principles emphasize speed, country ownership, targeted resource use, evidence-informed decision-making, coordination, and sustainability.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) issued an Annual Program Statement Addendum for Rapid Outbreak Response (ROR), inviting organizations to submit Statements of Interest (SOI) for projects supporting countries in responding to infectious disease outbreaks. This initiative, part of the America First Global Health Strategy, aims to detect outbreaks within seven days and contain them at their source, safeguarding the U.S. economy and health. The program seeks to enable timely, effective responses during early outbreak stages, prioritizing speed, operational readiness, and flexibility. Projects should provide life-saving support across various technical and operational domains, reinforce critical country systems, and demonstrate operational feasibility in high-risk environments. Key objectives include rapid activation, early detection and containment, coordinated response, and system reinforcement. Up to 10 awards, totaling $290M, are anticipated, with SOIs due by May 31.

The Department of State's APS Round 1 Q&A clarifies formatting, process, and submission requirements for Statements of Interest (SOIs) for the Advancing Global Health APS, particularly for the Child Protection and Rapid Outbreak Response Addenda. Key clarifications include a five-page narrative limit for SOIs, with critical details, tables, charts, and up to four single-page annexes excluded from this limit. The review process involves technical eligibility, merit panel evaluation, and internal clearance, with results communicated as not selected, recommended for consultative program design, or invited to Phase 2 (full application). Submissions are accepted via Grants.gov or MyGrants, with standard federal forms not required at the SOI stage. Neither Addendum has priority countries or pathogens, and SOIs can focus on one or multiple objectives and are not limited to countries with existing MOUs. The Child Protection Addendum covers children ages 0-17 (with a focus on 0-2 for malnutrition) and allows for flexibility in approaches and objectives. The Rapid Outbreak Response Addendum emphasizes rapid detection and containment within seven days, welcoming diverse approaches and coordination with existing initiatives.

The Department of State's APS Round 1 Q&A clarifies formatting, process, timeline, and submission platform details for Statements of Interest (SOIs) in federal grants. It outlines a five-page limit for the narrative, excluding cover pages, tables, charts, and up to four one-page annexes. The review process involves technical eligibility, merit panel evaluation, and internal clearance, with outcomes communicated in a timely manner, though individual feedback is not provided. SOIs are submitted via Grants.gov or MyGrants, with standard federal forms not required at the SOI stage. The document also addresses specific questions for "Child Protection" and "Rapid Outbreak Response" addenda, emphasizing that proposals are not limited to countries with existing MOUs, can focus on single objectives, and should align with the America First Global Health Strategy. It encourages broad scope within the addendum's objectives, supporting diverse approaches and ages for child protection, and various outbreak response strategies.

The Department of State's APS Round 1 Q&A clarifies formatting, process, and timeline for Statements of Interest (SOIs) for the Advancing Global Health APS, particularly for Child Protection and Rapid Outbreak Response Addenda. SOIs for the narrative portion are limited to five pages, with tables, charts, and a cover page excluded from this limit. Up to four one-page annexes are allowed. The review process involves technical eligibility, merit review, and internal clearance, with notifications of outcomes but no individualized feedback for unsuccessful applicants. Submissions are accepted via Grants.gov or MyGrants, with standard federal forms not required for the SOI stage. Proposed activities under both addenda are not limited to countries with existing MOUs, and applicants can focus on one or multiple objectives. The Child Protection Addendum covers children ages 0-17 (with a specific focus on 0-2 for malnutrition prevention) and does not specify priority countries or a minimum/maximum number of countries for proposals. The Rapid Outbreak Response Addendum prioritizes early detection and containment, welcoming proposals for various technical domains and not limiting submissions to MOU countries or specific pathogens. Funding details and award types are subject to the review process and Phase 2 applications.

The Department of State's APS Round 1 Q&A clarifies formatting, process, timeline, and submission platform requirements for Statements of Interest (SOIs) in federal grants. It details page limits, the exclusion of cover pages and visual elements from the narrative count, and annex guidelines. The review process involves technical eligibility, merit panel evaluation, and internal clearance, with results communicated as 'not selected,' 'recommended for consultative program design,' or 'recommended for full application.' Submissions are accepted via Grants.gov (requiring SF-424 forms for system purposes only, not review) or MyGrants (no SF-424 required). The document also addresses specific inquiries for two addenda: Child Protection and Rapid Outbreak Response. Both addenda encourage broad scope within their objectives, do not require MOUs for all countries, and allow focus on single objectives. Funding details and award types are subject to the review process.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) invites Statements of Interest (SOIs) for projects to implement the Health Foreign Assistance Memorandum of Understanding (MOU) with the Government of Malawi (GOM). This initiative, part of the “Advancing Global Health” Annual Program Statement, seeks to transition Malawi towards sustainable, integrated, and accountable health systems. Up to four awards, totaling an estimated $35M annually, are anticipated. Projects should be completed within five years and focus on strengthening health systems, supply chains, and data integration. The three key objectives include providing strategic assistance to strengthen national and district-level health capacities for government-led service delivery, enhancing Malawi's integrated health commodity supply chain, and bolstering data systems integration for improved decision-making. The program prioritizes sustainability, country ownership, continuity of life-saving services, and evidence-based approaches, aligning with U.S. foreign policy goals.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) invites Statements of Interest (SOIs) for projects to implement a Health Foreign Assistance Memorandum of Understanding (MOU) with the Government of Malawi (GOM). This initiative, under the "Advancing Global Health" program, seeks to support Malawi's transition to sustainable, integrated, and accountable health systems. The program, with an estimated annual funding of up to $35 million for up to four awards, focuses on strengthening epidemic control, improving service delivery, reinforcing health security, and advancing country ownership. Projects should align with three main objectives: strengthening MOHS, MoFEPD, and district-level capacity for integrated service delivery; enhancing the GOM's integrated health commodity supply chain system; and bolstering data systems integration and interoperability for data-driven decision-making. Key principles include promoting sustainability, ensuring continuity of life-saving services, using evidence-based approaches, strengthening integrated systems, leveraging local partnerships, and ensuring oversight and coordination.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy invites Statements of Interest for projects implementing the Health Foreign Assistance Memorandum of Understanding (MOU) in Malawi. This addendum to the “Advancing Global Health” Annual Program Statement seeks proposals to support Malawi's transition to sustainable, integrated, and accountable health systems. Up to four awards, totaling an estimated $35 million annually, will fund projects lasting five years or less. The initiative focuses on strengthening epidemic control, improving service delivery, reinforcing health security, and advancing long-term country ownership under the U.S. Government–Government of Malawi MOU Implementation Plan (April 2026–December 2030). Key objectives include providing strategic assistance to strengthen national and district-level health system capacity (MOHS, MoFEPD), enhancing integrated health commodity supply chains, and reinforcing data systems integration for improved decision-making. Projects must promote sustainability, ensure continuity of life-saving services, utilize evidence-based approaches, strengthen integrated systems, and leverage local partnerships.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) invites Statements of Interest (SOIs) for projects to implement a Health Foreign Assistance Memorandum of Understanding (MOU) with the Government of Malawi (GOM). The initiative, titled "Advancing Global Health" (Funding Opportunity Number DFOP0017890), aims to transition Malawi towards sustainable, integrated, and accountable health systems by supporting the USG–GOM MOU Implementation Plan (April 2026–December 2030). Up to four awards, totaling an estimated $35M annually, will be granted for projects lasting five years or less. Key objectives include strengthening GOM capacity for integrated service delivery (Objective 1), enhancing the health commodity supply chain (Objective 2), and improving data systems integration and interoperability for data-driven decision-making (Objective 3). The program emphasizes sustainability, country ownership, continuity of life-saving services, evidence-based interventions, integrated systems, and collaboration with local partners, while ensuring separation of religious activities for faith-based organizations.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy (GHSD) invites Statements of Interest (SOIs) for projects to implement the Health Foreign Assistance Memorandum of Understanding (MOU) with the Government of Malawi (GOM). This addendum to the "Advancing Global Health" Annual Program Statement seeks SOIs for a two-step application process, with up to four awards totaling $35 million annually over five years. The program aims to transition Malawi to sustainable, integrated, and accountable health systems by strengthening epidemic control, improving service delivery, reinforcing health security, and advancing country ownership. Objectives include strengthening the Ministry of Health and Sanitation (MOHS) and district-level capacity for integrated service delivery, enhancing the GOM's health commodity supply chain, and improving data systems integration for data-driven decision-making. Proposed interventions must promote sustainability, ensure continuity of life-saving services, utilize evidence-based approaches, strengthen integrated systems, and leverage local partnerships.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy invites Statements of Interest for projects supporting the implementation of the U.S. Government–Government of Uganda (GOU) Memorandum of Understanding (MOU) Implementation Plan (April 2026–December 2030). This initiative, titled "Health Foreign Assistance Memorandum of Understanding (MOU) Implementation in Uganda," aims to transition Uganda towards sustainable, integrated, and accountable health systems. With up to $60,000,000 available across 15 awards, the program focuses on strengthening epidemic control, improving service delivery, reinforcing health security, and advancing long-term country ownership. It seeks partners for two tracks: "Sustainable Faith- and Community-Based Health Systems" and "Enabling Systems for Accountable, Government-Led Programming," encompassing eight objectives. Key objectives include establishing sustainable community-based health financing, sustaining integrated service delivery in faith-based facilities, building organizational capacity, strengthening digital health systems, expanding sustainable power solutions, institutionalizing supply chain accountability, conducting risk assessments for performance-based financing, and providing IRS quality assurance. The deadline for questions is June 17, 2026, and SOIs are due by July 31, 2026.

The U.S. Department of State's Bureau of Global Health Security and Diplomacy invites Statements of Interest for projects supporting the implementation of a Memorandum of Understanding with the Government of Uganda. The goal is to transition Uganda towards sustainable, integrated, and accountable health systems by strengthening epidemic control, improving service delivery, reinforcing health security, and advancing country ownership. The initiative, active from April 2026 to December 2030, aims to build a resilient health system through two tracks: supporting sustainable faith- and community-based health systems and enabling accountable, government-led programming. The total available funding is up to $60,000,000 for up to 15 awards, with projects to be completed in five years or less. Submissions should align with principles of sustainability, continuity of life-saving services, data utilization, integrated systems, local partnerships, evidence-based approaches, and coordination with Ugandan institutions.