The National Institutes of Health (NIH) is announcing a funding opportunity for the establishment of a Dental Primary Care Practice-Based Research Network (PBRN) through a cooperative agreement aimed at creating an Administrative and Resource Center (ARC). The ARC will facilitate the planning and implementation of observational studies and clinical trials focused on integrating oral health care into overall medical care, thereby promoting whole-person health. This initiative is crucial for enhancing research capabilities in dental primary care settings and will involve recruiting practitioners, managing a single Institutional Review Board (IRB), and providing necessary training for study participation across various U.S. regions. Interested applicants can reach out to Dena Fischer at dena.fischer@nih.gov or call 301-594-4876 for further information. The estimated synopsis post date is March 2, 2026, with applications expected to be solicited by May 25, 2026, and the anticipated award date is April 30, 2027.