GrantPostedDiscretionary

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

National Institutes of Health
PAR-27-039
Application Deadline
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Grant Opportunity Analysis

The National Institutes of Health, with participation from CDC components, is preparing a Small Business Innovation Research grant opportunity to support early-career scientists transitioning into entrepreneurship through the Small Business Transition Grant for New Entrepreneurs. The program will fund research and development at eligible U.S. small business concerns and place major emphasis on entrepreneurial training, mentoring, and career development for the principal investigator. It is limited to first-time principal investigators who are U.S. citizens or lawful permanent residents, and applications must include a mentor with measurable effort committed to the project. Applications are not being solicited yet, but the estimated synopsis post date is November 5, 2026, the estimated close date is January 5, 2027, and the grantor contact is NIH SEED at SEEDinfo@nih.gov or 301-827-8595.

Eligible Applicants

Small Businesses
Additional Eligibility Information

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.

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Project Timeline

postedOriginal Opportunity PostedMay 27, 2026

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

Name
NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER)

CFDA Numbers

93.879

Official Sources