The National Institutes of Health (NIH) is announcing a forthcoming opportunity for small businesses to apply for the NIDCR Small Research Grants aimed at dental, oral, and craniofacial health-related data analyses and the development of statistical or computational methodologies. This grant will support meritorious research projects that propose secondary analyses of existing databases or the development of novel analytical approaches, although applications are not currently being solicited. The initiative is crucial for advancing research in dental and craniofacial health, encouraging investigators to prepare collaborative and responsive projects ahead of the official announcement. Interested applicants can reach out to Lorena Baccaglini, DDS, MS, PhD, at lorena.baccaglini@nih.gov or by phone at 301-435-7908 for further information, with the estimated synopsis posting date set for June 16, 2025, and the application deadline anticipated for October 16, 2025.