Center of Excellence for Systems Modeling of Infection and Immunity across Biological Scales (U54 Clinical Trial Not Allowed) National Institutes of Health
The National Institutes of Health (NIH) has posted a grant opportunity titled "Center of Excellence for Systems Modeling of Infection and Immunity across Biological Scales (U54 Clinical Trial Not Allowed)". This grant aims to support the establishment of a Center of Excellence (CoE) that will coordinate the research community of infectious and immune-mediated disease (IID) computational modelers and advance IID modeling research across biological scales.
The CoE will include three coordinating cores and two research projects to advance and integrate bridge models across scales in the context of IID, including HIV/AIDS. The main objective of the CoE is to accelerate multi-scale model development, sharing and re-use, and support collaboration to benefit the entire IID research community.
The grant does not require cost sharing or matching requirements and falls under the category of funding activity for health. It is a cooperative agreement type of funding instrument. The opportunity is open to "Other Eligible Applicants" which include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), Non-domestic (non-U.S.) Entities (Foreign Organizations), Regional Organizations, Tribally Controlled Colleges and Universities (TCCUs), U.S. Territory or Possession. However, Non-domestic (non-U.S.) Entities (Foreign Organization) and non-U.S. components of U.S. Organizations are not eligible to apply.
The grant opportunity has a closing date of July 30, 2024, and the last updated date was March 13, 2024. The description of the grant provides detailed information on the purpose and requirements of the CoE. For further inquiries, interested parties can contact NIH Grants Information at grantsinfo@nih.gov. More information about the grant can be found at the following link: [http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-23-077.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-23-077.html).
Human Leukocyte Antigen (HLA) and Killer-cell Immunoglobulin-like Receptor (KIR) Region Genomics in Immune-Mediated Diseases (U01 Clinical Trial Not Allowed) National Institutes of Health
The National Institutes of Health (NIH) has posted a grant opportunity titled "Human Leukocyte Antigen (HLA) and Killer-cell Immunoglobulin-like Receptor (KIR) Region Genomics in Immune-Mediated Diseases (U01 Clinical Trial Not Allowed)". This grant aims to support research in three main areas: 1) defining associations between variations in HLA and KIR genetic regions and immune-mediated diseases, 2) elucidating mechanisms underlying these associations to advance therapeutic opportunities, and 3) validating association data to improve the predictive power of clinical disease screening.
The grant is a Cooperative Agreement and falls under the category of Health. The funding opportunity does not require cost sharing or matching. The maximum award ceiling is $400,000. The grant is open to various eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), Non-domestic (non-U.S.) Entities (Foreign Organizations), Regional Organizations, Tribally Controlled Colleges and Universities (TCCUs), U.S. Territory or Possession. However, non-domestic (non-U.S.) Entities (Foreign Organizations) and non-domestic components of U.S. Organizations are not eligible to apply.
The grant opportunity will close on August 20, 2024, and the archive date is set for September 25, 2024. For more information and to apply, interested parties can visit the following website: [http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-017.html](http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-017.html). If there are any inquiries, they can be directed to NIH Grants Information at grantsinfo@nih.gov.
Integrated Preclinical / Clinical AIDS Vaccine Development Program (IPCAVD) (U19 Clinical Trial Not Allowed) National Institutes of Health
The National Institutes of Health (NIH) is offering a federal grant opportunity titled "Integrated Preclinical / Clinical AIDS Vaccine Development Program (IPCAVD) (U19 Clinical Trial Not Allowed)". This grant aims to support the translation of advanced HIV-1 vaccine candidates from pre-clinical studies through different phases of process and product development, including Current Good Manufacturing Practice (CGMP) manufacturing and regulatory filing for clinical testing.
The grant will provide funding for various activities such as technology transfer, preclinical immunogenicity and optimization studies, process development, analytical assay development, qualification, validation, testing, small scale pilot or engineering runs, CGMP manufacture in partnership with Pharma/Biotech/Contract Manufacturing Organizations (CMO), quality assurance/quality control oversight, fill-finish activities, product release and storage, generation of reference standard, drug substance and drug product stability testing programs, Investigational New Drug (IND)-enabling studies, and regulatory submission preparation.
The grant opportunity falls under the category of Health and is classified as a Cooperative Agreement. The funding does not require cost sharing or matching. The maximum award ceiling for this grant is $3,000,000. The eligibility for this grant is open to various entities, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), Eligible Agencies of the Federal Government, Faith-based or Community-based Organizations, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments (Other than Federally Recognized), Non-domestic (non-U.S.) Entities (Foreign Organizations), Regional Organizations, Tribally Controlled Colleges and Universities (TCCUs), and U.S. Territory or Possession.
The closing date for this grant opportunity is March 14, 2025, and the archive date is April 19, 2025. For more information and to apply, please visit the following link: [Integrated Preclinical / Clinical AIDS Vaccine Development Program (IPCAVD) Grant](http://grants.nih.gov/grants/guide/pa-files/PAR-23-033.html). If you have any inquiries, you can contact NIH Grants Information at grantsinfo@nih.gov.
NIAID Resource-Related Research Projects (R24 Clinical Trial Not Allowed) National Institutes of Health
The National Institutes of Health (NIH) is offering a grant opportunity titled "NIAID Resource-Related Research Projects (R24 Clinical Trial Not Allowed)". This grant aims to support investigator-initiated Resource-Related Research Projects that provide coordination and support to high priority projects in need. The proposed resources should be relevant to the scientific areas of the NIAID mission, including the biology, pathogenesis, and host response to microbes, immune function and dysfunction, and translational research for the prevention and treatment of infectious, immune-mediated, and allergic diseases. The grant does not require cost sharing or matching and is open to various eligible applicants. The deadline for application submission is January 7, 2026. For more information and to apply, please visit the following link: [NIAID Resource-Related Research Projects Grant](http://grants.nih.gov/grants/guide/pa-files/PAR-23-065.html). For any inquiries, please contact NIH Grants Information at grantsinfo@nih.gov.
Resource-Related Research Projects for Development of Animal Models and Related Materials (R24 Clinical Trials Not-Allowed) National Institutes of Health
The National Institutes of Health (NIH) is offering a grant opportunity titled "Resource-Related Research Projects for Development of Animal Models and Related Materials." This grant aims to support the development, characterization, and improvement of animal models of human diseases, as well as improving access to information about these models and enhancing the diagnosis and control of diseases in laboratory animals.
The funded projects should focus on creating animal models, related materials, or technological tools that have broad applicability to the scientific interests of two or more NIH Institutes or Centers (ICs). These models should evaluate diseases and processes that impact multiple body systems, aligning with the NIH Office of Research Infrastructure Programs' (ORIP) mission and programs.
Applicants must demonstrate the need for and potential impact of the proposed resources on the research community across various scientific disciplines supported by multiple NIH ICs. Projects that are limited to a specific disease or a narrow area of research, or that do not have a broad impact on the NIH-wide research community, will not be considered acceptable.
The grant opportunity does not require cost sharing or matching funds. Eligible applicants include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), eligible agencies of the federal government, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Indian/Native American Tribal Governments, non-domestic (non-U.S.) entities (foreign organizations), regional organizations, Tribally Controlled Colleges and Universities (TCCUs), U.S. territories or possessions. Non-domestic (non-U.S.) entities (foreign institutions) and non-domestic components of U.S. organizations are not eligible to apply.
The closing date for applications is May 25, 2025. For more information and to apply, interested parties can visit the following website: [Resource-Related Research Projects for Development of Animal Models and Related Materials](http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-22-013.html). Any inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov.