NIH Directors Transformative Research Awards (R01 Clinical Trial Optional)
ID: 358874Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/358874

Additional Information

http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-25-003.html
Timeline
    Description

    The National Institutes of Health (NIH) is offering the NIH Directors Transformative Research Awards, a federal grant opportunity aimed at supporting innovative and groundbreaking research that has the potential to significantly alter scientific paradigms or improve clinical approaches. This program encourages applications from individual scientists or groups proposing bold research across various disciplines relevant to the NIH mission, with no preliminary data required for submission. Approximately $8 million is available for Fiscal Year 2026, targeting around seven awards, each with a maximum project period of five years, and key deadlines include an opening date on August 3, 2025, and a submission deadline of September 4, 2025. Interested applicants can find more information and guidelines at the NIH Grants website or contact NIH Grants Information at grantsinfo@nih.gov for inquiries.

    Point(s) of Contact
    grantsinfo@nih.gov
    Files
    Title
    Posted
    RFA-RM-25-003-Full-Announcement.html
    RFA-RM-25-003.html
    The National Institutes of Health (NIH) is announcing the NIH Director's Transformative Research Awards under a Common Fund initiative, aiming to support groundbreaking research with the potential to significantly alter scientific paradigms or improve clinical approaches. This funding opportunity encourages applications from individual scientists or groups proposing innovative research across diverse disciplines relevant to NIH's mission, without requirement for preliminary data. Approximately $8 million will be available in Fiscal Year 2026, targeting about seven awards, each with a maximum project period of five years, depending on available appropriations and merit of submissions. Key application deadlines include an opening date on August 3, 2025, and a submission deadline of September 4, 2025. Eligible applicants range from higher education institutions to federal government entities. The review process emphasizes significance, innovation, and feasibility, seeking to identify research with extraordinary transformative potential. Applicants must adhere to specific submission guidelines and registration requirements, emphasizing robust planning despite high-risk research. The initiative underscores NIH's dedication to advancing innovative approaches that address entrenched scientific challenges and enhance public health outcomes.
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