Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
Grant Opportunity Analysis
The National Institutes of Health, through the National Heart, Lung, and Blood Institute, is seeking applications for a Data Coordinating Center to support investigator-initiated multi-site clinical trials under a cooperative agreement. The DCC is expected to provide overall project coordination, administration, data management, and biostatistical support for the trial proposed with the companion Clinical Coordinating Center application, including collaboration on the community engagement plan. The opportunity emphasizes milestone-driven management, innovative trial designs, and strong trial coordination and statistical expertise, with an expected five-year project period and no foreign subawards or subcontracts allowed in applications. Applications must be submitted in parallel with the companion CCC application on the same due date. The current close date is November 2, 2028, and the listed contact email is NHLBIDCVSClinical@mail.nih.gov.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.