Cooperative AgreementPostedDiscretionary

Viral INfections in the Young Lung- The VINYL Clinical Consortium (UG3/UH3 Clinical Trial Optional)

National Institutes of Health
RFA-HL-26-006
Application Deadline
Nov 10, 2025
Closed
Days Remaining
0
Deadline passed
Award Ceiling
Total Program Funding

Grant Opportunity Analysis

The National Institutes of Health (NIH) is inviting applications for the Viral INfections in the Young Lung (VINYL) Clinical Consortium, a cooperative agreement aimed at establishing a consortium of clinical sites to conduct a comprehensive observational study on viral lower respiratory tract infections (LRTI) in children aged 0-2 years. The primary objective is to deep phenotype 1500 hospitalized infants and toddlers with viral LRTI, followed by longitudinal assessments to evaluate long-term pulmonary outcomes, including asthma, and other developmental factors. This initiative addresses critical knowledge gaps in understanding the condition and its management, with a total funding availability of up to $2.624 million for one award over a maximum project period of seven years. Interested applicants must submit their proposals by November 10, 2025, and can direct inquiries to NIH Grants Information at grantsinfo@nih.gov.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grant Documents

2 Files
RFA-HL-26-006-Full-Announcement.html
HTML0 KBSep 21, 2025
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RFA-HL-26-006.html
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The Department of Health and Human Services, National Institutes of Health (NIH), and National Heart, Lung, and Blood Institute (NHLBI) are seeking applications for the Viral INfections in the Young Lung (VINYL) Clinical Consortium (UG3/UH3 Clinical Trial Optional). This Notice of Funding Opportunity (NOFO) aims to establish a Clinical Coordinating Center (CCC) with five Clinical Centers (CCs) and one Biorepository, as well as a companion Data and Analytics Coordinating Center (DACC). The consortium will conduct a seven-year observational cohort study to deep-phenotype 1500 children aged 0-2 years hospitalized with viral lower respiratory tract infections (LRTI) and follow them until preschool age to understand long-term pulmonary outcomes. The project also requires 2-4 prospective interventional mechanistic studies. The total funding available is up to $2.624 million in FY26 for one award, with a maximum project period of seven years. Eligible applicants include various organizations in the U.S., but foreign organizations are not eligible. Substantial federal involvement is expected, and data and biospecimens will be made publicly available to the research community.

Related Grant Opportunities

Project Timeline

postedOriginal Opportunity PostedSep 18, 2025
deadlineApplication DeadlineNov 10, 2025
expiryArchive DateDec 16, 2025

Funding Details

No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Cooperative Agreement

Grantor Contact

CFDA Numbers

93.838

Official Sources