The Centers for Disease Control and Prevention (CDC) is offering exploratory and developmental grants related to the World Trade Center Health Program (R21) to support research addressing diagnostic and treatment uncertainties for individuals affected by the 9/11 attacks. This funding opportunity aims to encourage innovative research projects that explore new areas of investigation, potentially leading to significant advancements in treatment effectiveness and diagnostic practices for those receiving monitoring and treatment under the James Zadroga 9/11 Health and Compensation Act. With an estimated total program funding of $30 million and an expected 60 awards, applicants can request funding ranging from $0 to $365,000. Interested parties should note that applications are due by 5:00 PM local time on February 12, 2026, and can direct inquiries to Dr. Eduardo O'Neill at 404-718-8844 or via email at fzt4@cdc.gov.