GrantPostedDiscretionary

NIH Director's Pioneer Award (DP1 Clinical Trial Optional)

National Institutes of Health
RFA-RM-28-001
Application Deadline
—
Days Remaining
—
Until deadline
Award Ceiling
$700,000
Total Program Funding
$8,200,000

Grant Opportunity Analysis

The National Institutes of Health is seeking applications for the NIH Director's Pioneer Award under the High-Risk, High-Reward Research Program. Selected grantees will pursue exceptionally creative and bold research projects that explore new scientific directions substantially different from their current research and existing work in the field. Eligible applicants include regional organizations, eligible federal agencies, U.S. territories, and foreign institutions conducting work relevant to the NIH mission. The agency estimates making seven awards, each with a flat funding amount of $700,000 in direct costs per year. Applications must be submitted by the estimated close date of September 9, 2027, and inquiries can be sent to PioneerAwards@mail.nih.gov.

Eligible Applicants

Others
Additional Eligibility Information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

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Project Timeline

postedOriginal Opportunity PostedSep 3, 2026

Funding Details

Award Ceiling
$700,000
Award Floor
$700,000
Est. Total Program Funding
$8,200,000
Expected Awards
7
No cost sharing required

Agency & Classification

Agency
National Institutes of Health(HHS-NIH11)
Funding Category
Health
Funding Instrument
Grant

Grantor Contact

Name
NIH Director's Pioneer Award Program

CFDA Numbers

93.310

Official Sources