Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)
ID: 360593Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes

Original Source

https://grants.gov/search-results-detail/360593
Timeline
    Description

    The National Institutes of Health (NIH) is offering the Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESIs), aimed at supporting fundamental, investigator-initiated research within the mission of the National Institute of General Medical Sciences (NIGMS). This grant program is designed to provide funding stability and scientific flexibility, allowing early career researchers to undertake ambitious studies while reducing administrative burdens by consolidating all NIGMS research support into a single award. The MIRA program is crucial for enhancing scientific productivity and fostering breakthroughs in health research, with no cost-sharing or matching requirements. Interested applicants can reach out to Michelle R. Bond, Ph.D. and Marc Rigas, Ph.D. at 301-594-2987 or via email at ESIMIRA@nigms.nih.gov for further information. The estimated project start date is July 1, 2027, with applications expected to close on October 5, 2026.

    Point(s) of Contact
    Michelle R. Bond, Ph.D. and Marc Rigas, Ph.D.
    (301) 594-2987
    ESIMIRA@nigms.nih.gov
    Files
    No associated files provided.
    Similar Opportunities
    Maximizing Investigators Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is inviting applications for the Maximizing Investigators' Research Award (MIRA) aimed at Early Stage Investigators (ESIs) under the Notice of Funding Opportunity (NOFO) PAR-23-145. This grant supports a comprehensive research program within the mission of the National Institute of General Medical Sciences (NIGMS), allowing eligible researchers to apply for up to $250,000 per year for a maximum of five years, with a requirement to dedicate at least 51% of their research efforts to the program. The MIRA program is designed to enhance scientific productivity and flexibility, enabling early-career scientists to explore significant research projects without the need for preliminary data, while also promoting diversity through a required Plan for Enhancing Diverse Perspectives (PEDP). Interested applicants should note that the application deadline is February 3, 2026, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    Maximizing Investigators' Research Award
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Maximizing Investigators' Research Award (MIRA), a federal grant aimed at supporting research within the mission of the National Institute of General Medical Sciences (NIGMS). This grant is designed to provide funding stability and scientific flexibility to eligible small businesses and NIGMS-funded investigators, thereby fostering innovative research and enhancing scientific productivity. The MIRA program has become a primary mechanism for supporting fundamental, investigator-initiated research, and encourages applications from both established and new investigators. Interested applicants can reach out to Baishali Maskeri, Ph.D., and Charles Ashley Barnes, Ph.D., at NIGMSEINIMIRA@NIGMS.NIH.GOV or by phone at 301-594-2752. The estimated synopsis close date is January 27, 2026, with awards expected to be made by December 1, 2026.
    Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Method to Extend Research in Time (MERIT) Award Extension, aimed at providing extended grant support to Early Stage Investigators (ESIs) who have shown strong research potential and received favorable evaluations on their R01 applications. This funding opportunity allows for up to seven years of support in two segments, enabling ESIs to establish their careers while focusing on critical cancer research areas such as identifying cancer risks, improving early detection strategies, and developing treatment methods. Interested applicants, including a diverse range of institutions such as Historically Black Colleges and Universities and Tribal Colleges, must adhere to specific application guidelines and register with Grants.gov and eRA Commons, with applications opening on February 3, 2025, and due by March 3, 2025. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Notice of Intent to Publish a Funding Opportunity Announcement for Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) intends to publish a Notice of Funding Opportunity (NOFO) for the Stephen I. Katz Early Stage Investigator Research Project Grant (R01), aimed at supporting early stage investigators (ESIs) in initiating research projects that diverge from their previous focus. Applicants must propose innovative research directions that do not build upon prior work, encouraging a shift in methodology, discipline, or therapeutic target, and are advised to consult with program directors regarding their proposals. This grant is crucial for fostering new scientific inquiries and advancing health-related research, with no cost-sharing requirements and an estimated award date of July 1, 2026. Interested applicants can reach out to the Division of Biomedical Research Workforce at NIH via email at nihtrain@mail.nih.gov or by phone at 301-496-0180 for further information, with applications expected to be submitted by September 26, 2025.
    Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity titled "Supporting Talented Early Career Researchers in Genomics," aimed at supporting innovative research projects led by Early Stage Investigators (ESIs) with a focus on genomics. This initiative encourages diverse applicants to propose research that aligns with the mission of the National Human Genome Research Institute (NHGRI), covering areas such as genomic sciences, genomic medicine, genomic data science, and the ethical implications of genomics. The program has a funding commitment of at least $2 million, with plans to award 3-5 grants, each with an annual budget cap of $400,000. Applications must be submitted electronically by February 26, 2027, and should include a detailed professional development plan and a resource sharing plan in compliance with NIH policies. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.
    Notice of Intent to Publish a Funding Opportunity Announcement for Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
    National Institutes of Health
    The National Institutes of Health (NIH) intends to publish a Notice of Funding Opportunity (NOFO) for the Stephen I. Katz Early Stage Investigator Research Project Grant (R01), aimed at supporting early-stage investigators (ESIs) in initiating innovative research projects. Eligible applicants, specifically small businesses, are encouraged to propose research that represents a significant change in their research direction, distinct from their previous work, and must involve basic experimental studies with human participants. This funding opportunity is crucial for advancing basic science research and is expected to open for applications on July 26, 2025, with a closing date of September 26, 2025, and an estimated award date of July 1, 2026. For further inquiries, interested parties can contact the Division of Biomedical Research Workforce at NIH via email at nihtrain@mail.nih.gov or by phone at 301-496-0180.
    Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed), aimed at supporting innovative research projects that signify a new direction for early stage investigators (ESIs). Applicants must propose projects without any preliminary data and align their research with the mission of participating NIH Institutes and Centers, while clinical trials are explicitly prohibited. This grant initiative is crucial for fostering innovation among ESIs, allowing them to explore novel research avenues over a maximum project period of five years. Interested applicants should note that the first application deadline is August 25, 2025, and can reach out to NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    NIGMS National and Regional Resources
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a federal grant opportunity titled "NIGMS National and Regional Resources," aimed at supporting resources that enhance biomedical research capabilities for a large number of investigators. This program seeks to provide access to state-of-the-art technologies and expertise, enabling substantial numbers of researchers to benefit from resources that may not be available at individual institutions. The grant is open to small businesses, with no cost-sharing or matching requirements, and is categorized under discretionary funding with an estimated award date of June 1, 2026. Interested applicants can reach out to Han Nguyen, Ph.D., at han.nguyen@nih.gov or call 301-594-4640 for further information, and should note that the application period will close on September 25, 2025.
    Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) to support innovative research projects led by early-stage investigators (ESIs) that represent a significant change in research direction without prior preliminary data. Applicants must submit proposals that do not include preliminary data and must describe the proposed shift in research focus, aligning with the missions of participating NIH Institutes and Centers. This grant aims to foster groundbreaking research and promote workforce diversity among ESIs from various backgrounds, including higher education institutions, nonprofits, and local governments. The application period opens on December 29, 2023, with a submission deadline of December 28, 2026. For further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov, and additional details can be found at the provided link: https://grants.nih.gov/grants/guide/pa-files/PAR-24-075.html.
    Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering the Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required) to support innovative research projects from early stage investigators (ESIs) that represent a new research direction and do not include preliminary data. Applicants must propose basic science experimental studies involving human participants, which align with NIH's definitions of both clinical trials and basic research, and must include a one-page attachment detailing the change in research direction. This grant opportunity is crucial for advancing fundamental biomedical and behavioral research without immediate application towards processes or products. The application period opens on August 25, 2025, and closes on August 25, 2028, with additional information available at NIH Grants. For inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.