DoD Breast Cancer Breakthrough Award Levels 1 and 2

The Department of Defense (DoD) announces the FY25 Breast Cancer Research Program (BCRP) Breakthrough Award Levels 1 and 2 to support innovative research aimed at significant advancements in breast cancer treatment and prevention. The funding opportunity, valued at approximately $37.7 million, aims to resolve overarching challenges related to breast cancer, including prevention, understanding metastasis, and enhancing treatment efficacy. Eligible applicants include both domestic and foreign nonprofit and for-profit organizations, with a focus on collaborative partnerships. The submission process consists of a two-step application, requiring a pre-application by June 13, 2025, and a full application by June 27, 2025. Key components for the application include detailed project narratives, specific aims, research strategies, and compliance with ethical guidelines concerning human subjects. Peer review will assess applications based on impact, research strategy, and personnel qualifications. The program emphasizes innovative approaches and collaborations, particularly those involving members of the military and veterans, highlighting the need for revolutionary strategies in addressing breast cancer challenges. This initiative exemplifies the government's commitment to advancing breast cancer research through substantial funding and structured evaluation processes.