ContractCombined Synopsis/SolicitationTotal Small Business Set-Aside (FAR 19.5)

Benchtop Microbial Bioreactor System

DEPARTMENT OF HEALTH AND HUMAN SERVICES 75F40125Q00352
Response Deadline
Aug 21, 2025
Deadline passed
Days Remaining
0
Closed
Set-Aside
Total Small Business Set-Aside (FAR 19.5)
Notice Type
Combined Synopsis/Solicitation

Contract Opportunity Analysis

The Department of Health and Human Services, specifically the Food and Drug Administration (FDA), is seeking quotes for the procurement of two complete benchtop microbial bioreactor systems. These systems are intended for use by the Office of Pharmaceutical Quality Research (OPQR) to cultivate Escherichia coli and assess the effects of cell extract preparation on the quality of human therapeutic proteins during cell-free protein synthesis (CFPS). The bioreactor systems must feature automated control and monitoring capabilities for various parameters, including temperature, pH, dissolved oxygen, foam levels, and turbidity, with a working volume of 10 liters for high-density E. coli culture. Interested small businesses must submit their quotes by 2:00 PM Eastern Time on August 21, 2025, via email to Janice Heard at janice.heard@fda.hhs.gov, as this opportunity is set aside for small businesses under FAR 19.5.

Classification Codes

NAICS Code
334516
Analytical Laboratory Instrument Manufacturing
PSC Code
6640
LABORATORY EQUIPMENT AND SUPPLIES

Solicitation Documents

1 Files
RFQ 75F40125Q00352 .docx
Word191 KB8/7/2025
AI Summary
The Food and Drug Administration (FDA) is issuing a Request for Quote (RFQ) No. 75F40125Q00352 for two complete benchtop bioreactor systems. These systems will be used by the Office of Pharmaceutical Quality Research (OPQR) to cultivate Escherichia coli and investigate the impact of cell extract preparation on human therapeutic protein quality during cell-free protein synthesis (CFPS). The bioreactor systems must be capable of automated control and monitoring of temperature, pH, dissolved oxygen, foam levels, and turbidity, with a 10 L working volume for high-density E. coli culture. The solicitation is a small business set-aside, and quotes are due by 2:00 PM Eastern Time on August 21, 2025, via email to Janice.Heard@fda.hhs.gov. The contract will be a firm fixed-price purchase order, with delivery and installation required at the FDA White Oak Campus in Silver Spring, MD. The document outlines detailed technical specifications, required accessories, and various Federal Acquisition Regulation (FAR) and HHS Acquisition Regulation (HHSAR) clauses pertaining to commercial items, payment, and accessibility.

Related Contract Opportunities

Project Timeline

postedOriginal Solicitation PostedAug 7, 2025
deadlineResponse DeadlineAug 21, 2025
expiryArchive DateAug 22, 2025

Agency Information

Department
DEPARTMENT OF HEALTH AND HUMAN SERVICES
Sub-Tier
FOOD AND DRUG ADMINISTRATION
Office
FDA OFFICE OF ACQ GRANT SVCS

Point of Contact

Name
Janice Heard

Place of Performance

Silver Spring, Maryland, UNITED STATES

Official Sources