The National Institute of Environmental Health Sciences (NIEHS), part of the Department of Health and Human Services, intends to negotiate a sole source contract with Qiagen, LLC for the IPA Analysis Match Explorer CL software, which is essential for their research needs. This unique software requirement is deemed to have only one responsible source capable of fulfilling the government's specifications, highlighting its critical role in NIEHS's operations. The contract is set for a performance period from January 1, 2026, to December 31, 2027, and interested parties who believe they can meet the requirements are encouraged to submit a capability statement by December 12, 2025, at 12:00 PM EST to Joseph Williams at joseph.williams2@nih.gov. No solicitation package is available, and the government's decision on whether to pursue a competitive procurement will be based on the responses received.