The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking information from vendors regarding the procurement of a liquid chromatography triple quadrupole mass spectrometry system with a thermal desorption-based ambient ionization source. This system is intended to support the Surface and Trace Chemical Analysis Group's efforts in analytical chemistry and mass spectrometry, particularly for applications in forensic science, public health, and homeland security, as part of the Rapid Drug Analysis and Research (RaDAR) program. Interested parties are invited to submit their capabilities and relevant experience by emailing Donald Graham at deg@nist.gov, with responses due by the specified deadline, as NIST anticipates issuing a Request for Quotation in the third quarter and awarding a contract by the fourth quarter of FY2025. The small business size standard for this opportunity is 1,000 employees, and responses should adhere to the specified formatting guidelines.