NIH Tetramer Core Facility

Amendment No. 1 for RFP # 75N93026R00006,

The NIH Tetramer Core Facility (RFP Number: 75N93026R00006) seeks proposals for managing and operating a facility to produce and distribute antigenic peptide/MHC reagents for detecting antigen-specific T cells. The contract, issued on April 22, 2026, requires offerors to submit proposals by June 22, 2026, valid for 120 days. Key responsibilities include ongoing process optimization, maintaining a secure database for reagent requests, and operating a public-facing website. The contract period is from March 21, 2027, to March 20, 2028, with potential options for up to seven years. Offerors must be registered in SAM prior to award and submit various reports, including technical progress, financial conflict of interest, and Section 508 annual reports. Strict compliance with NIH policies on reproducibility, public access, and human subjects is mandatory. Financial terms include detailed invoice breakdowns and adherence to salary rate limitations. The solicitation emphasizes accessibility for information and communication technology and outlines guidelines for subcontracting, publications, and reporting fraud.