Synthesis of Substances for Pharmacological Testing

This combined synopsis/solicitation (Solicitation Number: D-26-DO-0018) is issued by the Drug Enforcement Administration (DEA) as an unrestricted Request for Quotation (RFQ) for the "Synthesis of Substances for Pharmacological Testing." The procurement falls under NAICS code 325199 (All Other Basic Organic Chemical Manufacturing) with a size standard of 1,250 employees. The requirement consists of 15 commercial line items of synthesized chemical compounds—primarily hydrochloride salts, opioid derivatives, and benzodiazepines—in quantities ranging from 200 mg to 1 gram. Specific target compounds include N-sec-butyl Butylone, Methiodone, Spirofluorphine, Methoxyorphine, and Cyclopropylflualprazolam, among others. Key administrative details and deadlines include: - **Questions Deadline:** September 23, 2026, at 2:00 PM EST, directed to Contracting Officer Angel Barkley. - **Solicitation Closing Date:** September 25, 2026, at 5:00 PM EST. - **Required Delivery Date:** January 31, 2027. The solicitation incorporates standard federal provisions and commercial clauses, including FAR 52.212-1, FAR 52.212-3, and DOJ-06 (National Security Risk Assessment), which requires offerors to submit supply chain risk assessment questionnaires. Award will be made to the responsible offeror whose conforming quote is most advantageous to the government, considering price and other evaluated factors.