Computer Programming ITDASS
ID: NB644040-25-01645Type: Combined Synopsis/Solicitation
Overview

Buyer

COMMERCE, DEPARTMENT OFNATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGYDEPT OF COMMERCE NISTGAITHERSBURG, MD, 20899, USA

NAICS

Other Computer Related Services (541519)

PSC

IT AND TELECOM - BUSINESS APPLICATION/APPLICATION DEVELOPMENT SUPPORT SERVICES (LABOR) (DA01)

Set Aside

Total Small Business Set-Aside (FAR 19.5) (SBA)
Timeline
    Description

    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking quotations for computer programming support to enhance its high-speed, high-volume cell imaging capabilities. The project aims to develop computational methods and tools for automating the processing and analysis of large datasets generated from biological imaging, which are crucial for advancements in drug development and personalized medicine. The selected contractor will be responsible for improving the existing image processing pipeline through specific tasks, including integrating advanced algorithms and maintaining strict documentation and quality control. Quotations must be submitted via email by July 3, 2025, and interested parties can contact Lisa Stevens at lisa.stevens@nist.gov for further information.

    Point(s) of Contact
    Files
    Title
    Posted
    The National Institute of Standards and Technology (NIST) seeks computer programming support for enhancing its high-speed, high-volume cell imaging capabilities, led by the Biosystems and Biomaterials Division (BBD). The project aims to develop computational methods and tools to automate the processing and analysis of large datasets generated from biological imaging, which are critical for advancements in drug development and personalized medicine. The contractor will improve the existing image processing pipeline through four specific tasks: integrating advanced 3D U-Net code for identifying mitosing cells, implementing a tracking routine for cell objects over time, enhancing the metadata schema for detailed image processing information, and reporting progress regularly. The contractor is required to maintain strict documentation and quality control, conducting regular updates and meetings with BBD scientists. The period of performance is set for six months at NIST's Gaithersburg, MD campus, with opportunities for telework. The contractor must possess significant qualifications in computer programming, data analysis, and image processing. This initiative underscores the need for advanced computational resources in facilitating next-generation biological investigations and applications.
    The National Institute of Standards and Technology (NIST) has issued a Request for Quotation (RFQ) No. NB644040-25-01645 for computer programming support in quantitative, high-speed, high-volume cell imaging. This RFQ falls under NAICS code 541519, covering Other Computer Related Services, with a revenue threshold of $34 million for small businesses. Responses are invited from recipients of NIST's Multiple Award IDIQ Contracts. Quotations must be submitted via email by July 3, 2025, and must include a technical and business response. The evaluation criteria for awarding the task order emphasize technical capability, past performance, and price, with non-price factors being equally important. Offerors are required to demonstrate their understanding of the project and either have relevant past performance or be rated neutral if lacking. The RFQ includes special provisions regarding supply chain security, invoicing instructions, and contractor security processing requirements due to the nature of government contracting. This RFQ underscores NIST’s initiative to enhance scientific research through advanced technology solutions and reflects the agency's commitment to incorporating quality and compliance measures in its procurement processes.
    Lifecycle
    Title
    Type
    Combined Synopsis/Solicitation
    Similar Opportunities
    Sources Sought Notice for Mid-IR Optical Frequency Comb
    Commerce, Department Of
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), has issued a Sources Sought Notice for Mid-IR Optical Frequency Comb Systems to support its CHIPS Metrology Program's Grand Challenge 1. NIST requires three systems for applications in broadband spectroscopy, spectral reference databases, and new laser diagnostics in semiconductor processes, along with an additional system to fill a critical gap in long-wave infrared spectroradiometry and molecular spectroscopy for the space, defense, and satellite industries. Interested vendors are invited to provide information regarding their capabilities, including product specifications, customization options, and available services, while ensuring that proprietary information is not disclosed. Responses should be submitted via email to Forest Crumpler at forest.crumpler@nist.gov, as NIST seeks to gather market insights to inform future procurement decisions.
    Sources Sought Notice for Continuous Wave Parametric Oscillator (CW OPO) Laser System
    Commerce, Department Of
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking information regarding a Continuous Wave Parametric Oscillator (CW OPO) Laser System to fulfill specific technical requirements. The desired system must include a pump laser, signal and idler laser outputs with defined tunable ranges and power, control electronics compatible with U.S. power and Windows PCs, as well as a high-accuracy wavelength meter and stabilization controls. This procurement is crucial for advancing analytical laboratory capabilities, and interested vendors are encouraged to submit their company details, equipment specifications, and service offerings by email to Forest Crumpler at forest.crumpler@nist.gov by October 31, 2022. This notice serves as market research and does not constitute a solicitation or commitment to award a contract.
    Protect Premium Service Agreement on ZEISS LSM 880 and Axio Observer 7 Microscopes
    Health And Human Services, Department Of
    The National Institutes of Health (NIH), specifically the National Institute on Drug Abuse (NIDA), is seeking qualified small businesses to provide a Protect Premium Service Agreement for ZEISS LSM 880 and Axio Observer 7 microscopes. The required services include preventative maintenance, on-demand repairs, software updates, technical telephone consultations, unlimited on-site visits, and access to proprietary parts and OEM-certified technicians. This procurement is crucial for maintaining the functionality of laboratory equipment used in research related to substance use disorders. Interested businesses must submit electronic capability statements by January 5, 2026, at 1:00 p.m. EST to Andrew Varley at andrew.varley@nih.gov, as this notice serves to gather information for determining the appropriate acquisition method and potential set-asides.
    Sole Source Justification Field Emission Scanning Electron Microscope (FESEM)
    Commerce, Department Of
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking to procure a Sole Source Field Emission Scanning Electron Microscope (FESEM) through a Justification for Other Than Full and Open Competition (JOFOC). This procurement is essential for advancing NIST's capabilities in laboratory equipment and supplies, particularly in high-resolution imaging and analysis. The justification for this sole source acquisition will be publicly available within 14 days of the contract award, and the opportunity will remain open for 30 days in accordance with federal regulations. Interested parties can reach out to Nina Lin at nina.lin@nist.gov or Forest Crumpler at forest.crumpler@nist.gov for further inquiries.
    Steller Sea Lion Artificial Intelligence Image Processing and Counting Enhancement Effort
    Commerce, Department Of
    The National Oceanic and Atmospheric Administration (NOAA) intends to negotiate a sole-source contract with Kitware, Inc. for the enhancement of artificial intelligence (AI) image processing and counting methods related to Steller sea lion populations in Alaska. The project aims to refine aerial imagery collection processes by improving existing detection and classification models, which are currently time-consuming and inaccurate, often relying on manual counting methods that can take up to four months. This initiative is crucial for effective conservation efforts, as it seeks to streamline monitoring processes and enhance data analysis capabilities for protected marine species. Interested vendors must submit their affirmative responses, demonstrating their understanding and capability to meet the requirements outlined in the Performance Work Statement, by 3:30 P.M. Pacific Standard Time on August 1, 2025, to Jamie Abu Shakrah at Jamie.AbuShakrah@noaa.gov.
    MRI physicist and scientist consultants
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH) through the Eunice Kennedy Shriver National Institute on Child Health and Human Development (NICHD), is seeking consultant services from MRI Physics and Engineering Consultants LLC for expertise in Magnetic Resonance Imaging (MRI) data acquisition and scanner pulse sequence programming. The objective of this procurement is to support an ongoing project focused on developing innovative medical imaging technologies aimed at the early diagnosis and treatment of chronic diseases associated with metabolic disorders and obesity. The selected consultant must hold a PhD in Bioengineering or a related field, possess over 15 years of relevant experience, and demonstrate proficiency in various programming and analysis software. Interested vendors are required to submit their quotations, including necessary documentation, to Kelly Robinson at Kelly.Robinson@nih.gov by January 12, 2026, at 12:00 PM, with the contract period of performance scheduled from March 30, 2026, to March 29, 2027.
    Service Agreement for NICHD Nikon AXR Confocal Microscope Equipment
    Health And Human Services, Department Of
    The National Institutes of Health (NIH) is seeking a service agreement for the maintenance and repair of a Nikon AXR Confocal Microscope, including associated components, for the National Institute of Child Health and Human Development (NICHD) in Bethesda, Maryland. The contract will cover a 12-month period, providing essential preventive maintenance, on-site repairs, laser alignments, genuine replacement parts, labor, and software updates to ensure the reliable operation of the equipment. This procurement is critical as it supports ongoing research activities that rely on the functionality of the microscope, with the anticipated award date set for April 1, 2026, and responses due by January 6, 2026, at 1700 Eastern Time. Interested parties should submit their proposals electronically to Jacob Balenson at jacob.balenson@nih.gov, referencing Presolicitation Number 75N94026Q00023 in the subject line.
    Sole Source Justification - Far-Infrared Dual Frequency Comb System
    Commerce, Department Of
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking to procure a Far-Infrared Dual Frequency Comb System through a sole source justification. This procurement aims to acquire specialized laboratory equipment and supplies that are critical for advancing research and development in precision measurement and metrology. The system is essential for various scientific applications, including spectroscopy and telecommunications, where high precision is required. Interested parties can reach out to Daniel Kent at daniel.kent@nist.gov or call 303-497-6533 for further information regarding this opportunity.
    Request for Information (RFI) Advanced Confocal and Super-Resolution Microscopy System
    Energy, Department Of
    The Department of Energy's Brookhaven National Laboratory (BNL) is seeking information from qualified vendors regarding an Advanced Confocal and Super-Resolution Microscopy System. The laboratory requires a unified platform that integrates confocal, fluorescence lifetime imaging (FLIM), and super-resolution nanoscopy (STED) capabilities, aimed at enhancing biological, chemical, and materials research through high-speed, multi-color fluorescence imaging. This procurement is critical for advancing imaging applications in various scientific fields, and interested vendors are invited to submit detailed technical and operational information by January 16, 2026, to Mark Brock at mbrock@bnl.gov.
    Multiple-Award Architect-Engineer Services
    Commerce, Department Of
    The Department of Commerce's National Institute of Standards and Technology (NIST) is seeking qualified architect-engineer firms to provide multiple-award A-E services for its facilities located in Colorado and Hawaii. The procurement aims to secure professional services for design, renovation, and construction projects, including specialized areas such as scientific research laboratories and hazardous material remediation, with a focus on mechanical, electrical, and plumbing (MEP) disciplines. This initiative is crucial for maintaining and enhancing NIST's operational capabilities across approximately 30 buildings, totaling around 650,000 square feet, which house various scientific and administrative functions. Interested firms must submit their responses by January 16, 2026, and can direct inquiries to Julie Morris at julie.morris@nist.gov or by phone at 303-497-6504.