The National Institute of Standards and Technology (NIST) seeks computer programming support for enhancing its high-speed, high-volume cell imaging capabilities, led by the Biosystems and Biomaterials Division (BBD). The project aims to develop computational methods and tools to automate the processing and analysis of large datasets generated from biological imaging, which are critical for advancements in drug development and personalized medicine. The contractor will improve the existing image processing pipeline through four specific tasks: integrating advanced 3D U-Net code for identifying mitosing cells, implementing a tracking routine for cell objects over time, enhancing the metadata schema for detailed image processing information, and reporting progress regularly. The contractor is required to maintain strict documentation and quality control, conducting regular updates and meetings with BBD scientists. The period of performance is set for six months at NIST's Gaithersburg, MD campus, with opportunities for telework. The contractor must possess significant qualifications in computer programming, data analysis, and image processing. This initiative underscores the need for advanced computational resources in facilitating next-generation biological investigations and applications.

The National Institute of Standards and Technology (NIST) has issued a Request for Quotation (RFQ) No. NB644040-25-01645 for computer programming support in quantitative, high-speed, high-volume cell imaging. This RFQ falls under NAICS code 541519, covering Other Computer Related Services, with a revenue threshold of $34 million for small businesses. Responses are invited from recipients of NIST's Multiple Award IDIQ Contracts. Quotations must be submitted via email by July 3, 2025, and must include a technical and business response. The evaluation criteria for awarding the task order emphasize technical capability, past performance, and price, with non-price factors being equally important. Offerors are required to demonstrate their understanding of the project and either have relevant past performance or be rated neutral if lacking. The RFQ includes special provisions regarding supply chain security, invoicing instructions, and contractor security processing requirements due to the nature of government contracting. This RFQ underscores NIST’s initiative to enhance scientific research through advanced technology solutions and reflects the agency's commitment to incorporating quality and compliance measures in its procurement processes.