NOI - Next Generation Sequencing Services for Detection of Somatic Genetic Mutations
Contract Opportunity Analysis
The National Heart, Lung, and Blood Institute, part of the National Institutes of Health within HHS, plans a sole source purchase order for next generation sequencing services to support clinical research on somatic genetic mutations associated with bone marrow failure syndromes. The work covers sequencing patient samples for detection of mutations relevant to bone marrow failure syndromes and hematologic disorders, with approximately 16 samples and results intended to support diagnosis, therapy planning, and ongoing research. The requirement includes a 302-gene sequencing panel, a 7–10 day turnaround time after sample receipt, and continuity with existing longitudinal research, with performance in Lake Forest, California; the action is under NAICS 541380 and is not set aside for small businesses. This is not a request for competitive quotations, but interested parties may submit capability statements by April 20, 2026 to Nicholas Capobianco at nicholas.capobianco@nih.gov.