Single Domain Antibody Development Service
Contract Opportunity Analysis
The National Institute of Diabetes and Digestive and Kidney Diseases, within the National Institutes of Health, is seeking a contractor to develop a custom single-domain antibody service targeting the human calcium-sensing receptor. The work is intended to support parathyroid tumor imaging, localization, and potentially radiopharmaceutical treatment for inoperable parathyroid cancer, with required deliverables of four purified, validated, 3XFLAG-tagged sdAb clones, four corresponding DNA minipreps, and complete protein and cDNA sequence information. The acquisition is a firm-fixed-price small business opportunity for performance in Bethesda, Maryland, with a period of performance of DOA plus six months and evaluation based on technical factors, past performance, and cost, with non-cost factors more important than price. Responses are due May 24, 2026 at 9:00 a.m. EDT under solicitation 75N98026Q00360, and the contracting contact is Towanda Daniels.